稍微爬了一些關於 COVID-19 疫苗的指引、疫苗混用、以及嚴重副作用的資料 (在年齡及性別有些有風險上的差異)。 如果有其他不錯的 reference, 也請幫忙多多提供。 ### 概觀指引 英國健保署的建議: "For people aged 40 or over and those with other health conditions, the benefits of being vaccinated with the Oxford/AstraZeneca vaccine outweigh any risk of clotting problems. For people under 40 without other health conditions, it's preferable to have the Pfizer/BioNTech or Moderna vaccine instead of the Oxford/AstraZeneca vaccine." https://www.nhs.uk/conditions/coronavirus-covid-19/coronavirus-vaccination/safety-and-side-effects/ ### 疫苗的說明 Information for UK recipients on COVID-19 Vaccine AstraZeneca ### 疫苗混用 "WHO warns against people mixing and matching COVID vaccines" https://www.reuters.com/business/healthcare-pharmaceuticals/who-warns-against-mixing-matching-covid-vaccines-2021-07-12/ "If it’s an option of either getting a mixed schedule or no second dose, then certainly go for the mixed schedule. multiple studies now back up the idea that mixing the Oxford–AstraZeneca jab and the Pfizer–BioNTech vaccine triggers an immune response similar to — or even stronger than — two doses of either vaccine." https://www.nature.com/articles/d41586-021-01805-2 ### 嚴重副作用: AZ "UK regulator says some evidence AstraZeneca clots occur more in women than men ... the difference in incidence was small" https://www.reuters.com/business/healthcare-pharmaceuticals/uk-regulator-says-some-evidence-astrazeneca-clots-occur-more-women-than-men-2021-05-06/ "just over 10 people develop this condition for every million doses of AZ vaccine given." (UK) https://www.gov.uk/government/publications/covid-19-vaccination-and-blood-clotting/covid-19-vaccination-and-blood-clotting "Estimated risk of TTS per 1,000,000 AstraZeneca vaccine doses (first dose): 19-31" (Australia) https://www.health.gov.au/initiatives-and-programs/covid-19-vaccines/is-it-true/is-it-true-does-the-astrazeneca-covid-19-vaccine-cause-blood-clots ### 嚴重副作用: mRNA 疫苗 (Moderna / Pfizer-BioNTech) "FDA to add warning about rare heart inflammation to Pfizer, Moderna vaccines ...much-higher-than expected number of young men between the ages of 12 and 24 have experienced heart inflammation after their second vaccine dose." https://www.reuters.com/business/healthcare-pharmaceuticals/us-panel-review-heart-inflammation-cases-after-pfizer-moderna-vaccines-2021-06-23/?fbclid=IwAR3EYjQ_fbVHwTyrfwPcqKaw38LU6XaoeGCgdtgLTcTtNJgopySAJMzw6ps "mRNA vaccines: ...approximately 40.6 cases of myocarditis per million second doses among males, and 4.2 cases per million among females" https://news.un.org/en/story/2021/07/1095622
